For Reader DC:
HKCU\Software\Adobe\Acrobat Reader\DC\Privileged DWORD Value: bProtectedMode Setting: 0x0
For Reader 11:
HKCU\Software\Adobe\Acrobat Reader\11.0\Privileged DWORD Value: bProtectedMode Setting: 0x0 There are “enterprise” keys that show up at HKLM that might work as well, but this has not been tested. For Reader DC, it is supposed to be: HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Adobe\Acrobat Reader\DC\FeatureLockDown