SAP Enhanced Global (Global Next) Integration & SAP S4/HANA 2020 Release Compatibility

I am currently using SAP Enhanced Global (Global Next) Integration Release 6.4.4.x, 6.4.5.x, or 6.5.x.x, and I am upgrading my SAP S4/HANA to 2020 Release; what are the procedures that I need to follow to guarantee compatibility?
Thomson Reuters always recommends that customers upgrade and use the most recent release of our products in order to leverage all enhancements that you are continuously adding, but if you are using SAP Enhanced Global (Global Next) Integration Release 6.4.4.x, 6.4.5.x, or 6.5.x.x and performing a SAP S4/HANA upgrade to 2020 Release, you have two options:
  1. Upgrade to our most recent release 6.6.2.0 that is fully compatible with SAP S4/HANA 2020; or
  2. Apply only a hotfix over your current 6.4.4.x, 6.4.5.x, or 6.5.x.x Release to make it compatible with SAP S4/HANA 2020. Open this zip file to get the hotfix package and view the steps to apply this hotfix.