United Kingdom

Name of Entity Registered Address Registered Number

Reuters Limited

The Thomson Reuters Building 30 South Colonnade Canary Wharf London E14 5EP United Kingdom 00145516

TR Organisation PLC

Aldgate House 33 Aldgate High Street London EC3N 1DL 2978875

Thomson Reuters Services Limited

5 Canada Square, Canary Wharf, London E14 5A 2316466

Centre for Medicines Research International Limited

Aldgate House 33 Aldgate High Street London EC3N 1DL England 04281417

Thomson Reuters (Professional) UK Limited

5 Canada Square, Canary Wharf, London E14 5A 01679046